The former Liverpool, Chelsea and Valencia boss watched his team progress with a 3-1 aggregate win against Dinamo Moscow in the last 16.
Ukrainian side Dynamo Kiev, who beat Everton to end English interest in European competition this season, will play Italian team Fiorentina.
Holders Sevilla are aiming to retain the trophy for a second time in 10 years, after also claiming back-to-back wins in 2005-06 and 2006-07.
The Spanish side face Russian club Zenit St Petersburg, while the other tie sees Ukraine's Dnipro Dnipropetrovsk take on Club Brugge of Belgium.
Ties will be played on 16 April and 23 April.
Full draw:
Sevilla v Zenit St Petersburg
Dnipro v Club Brugge
Dynamo Kiev v Fiorentina
Wolfsburg v Napoli
Tags
SOCCER
